Health Research - Mouse Models

  A new University of Iowa study suggests that metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis (MS), may provide protection against the disease. The study led by Ashutosh Mangalam, PhD, UI associate professor of pathology, shows that a diet rich in isoflavone, a phytoestrogen or plant-based compound that resembles estrogen, protects against multiple sclerosis-like symptoms in a mouse model of the disease. Importantly, the isoflavone diet was only protective when the mice had gut microbes capable of breaking down the isoflavones. The findings were published July 9 in  Science Advances . "Interestingly, previous human studies have demonstrated that patients with multiple sclerosis lack these bacteria compared to individuals without MS," Mangalam says. "Our new study provides evidence that the combination of dietary isoflavones and these isoflavone metabolizing gut bacteria may serve as a potential...

Today, GRAMMY, Golden Globe and Emmy-Award winning and multi-talented recording artist, actor, and producer Donald Glover a.k.a. Childish Gambino announced dates for his upcoming North American tour with special guest Rae Sremmurd . Produced by Live Nation in partnership with Wolf + Rothstein, the month-long outing will visit 13 cities across North America , kicking off in Atlanta on September 6 and wrapping in Vancouver on September 30.  Childish Gambino Unveils 2018 North American Tour With Special Guest Rae Sremmurd    Childish Gambino'...

JAY-Z AND BEYONCÉ are joining forces for the newly announced OTR II stadium tour. Kicking off Wednesday, June 6 th in Cardiff, UK , the international outing will stop in 15 cities across the UK and Europe and 21 cities in North America . The full itinerary can be found below. The tour is presented by Live Nation Global Touring in association with Parkwood Entertainment and Roc Nation. (PRNewsfoto/Live Nation Entertainment)... Tickets will go on sale to the general public starting ...

Clean Mic Green, also known as Mr Greenonit has just released the first single ‘Lite Green’ from his album ‘Green Blooded’. ‘Lite Green’ is a hard-hitting trap anthem with a hypnotic melody, booming bass and dancing hi-hats. The lyrics are braggadocios, the flow is faultless and the delivery is confronting. "Rollin dollo on da lo lo and that's quite clean, I do ma dirty by ma lonely since nineteen. And that's waay back like ma hairline(r), Nigga staay back ma peeps from Carolina” Mic raps, the lyrics are fierce in their boldness and paint a vivid picture. With signs Mic has been perfecting his craft for a long time, this is a lyricist with experience and maturity. The infectious melody of the chorus only inches you closer to developing an affinity with this enigmatic lyrical curator. The album ‘Green Blooded’ consists of twelve tracks and will be released in digital and physical format this spring through ‘Green Power’. ‘Green Power’ is the official brand n...

Yung Xander is a rapper from Connecticut that has been building momentum with his latest single ' Flexx' from the Circles EP. With mellow guitar sounds, trap-style percussion and deep melodic vocals, the atmosphere this track creates cannot be understated. Influenced by Lil Peep, GBC, Oliver Francis, Blink 182, Real Friends, the emo influence is strong and the result is something both ground-breaking and immersive. Xander has an innovative approach to creating; he has a natural presence on the mic and a flow that is vibrant and undeniably charismatic. With a buzz starting to build, Yung Xander is worth paying close attention.

Hall of Famers Set To Appear on Fox & Friends, Good Day NY, Varney & Company, Access Hollywood, PBS’s METRO FOCUS, IMUS in the Morning and more this week!! -- "There's a common thread linking the tracks, and gospel music in general: Humans locating the hope to be transported somewhere better.”​ - Jon Freeman, Rolling Stone Country "The Oak Ridge Boys have a deep history of gospel singing, and they have no trouble picking up the habit here." - Jeff Gage, Rolling Stone "The set is in fact an “organic” move for the Oaks, whose deep southern gospel music roots--along with early rock ‘n’ roll/R&B energy--have always been the bedrock of their unique country sound." – Jim Bessman, Centerline "An album that shows that, well in their fifth decade of recording and touring together, the ‘Mighty Oaks’ still have plenty of fuel in the creative ignition." – Chuck Dauphin, Sounds Like Nashville "You now have the perfec...

LSD Tour , featuring L ucinda Williams, S teve Earle, and D wight Yoakam, three highly esteemed artists who have garnered 49 GRAMMY nominations combined over the span of their illustrious careers. Sire Records recording artist King Leg will open the show as Special Guest. (PRNewsfoto/Live Nation Entertainment)... The North American tour, produced by Live Nation, unites three of music's most celebrated and iconic voices on one epic cross-country package for the very f...